The 42-year-old actress has recently been diagnosed with Cushing syndrome, a disorder that develops when the human body manufactures an excess of cortisol, a natural hormone in the body released during instances of stress. Signs and symptoms include rapid weight gain, high blood pressure, and bone loss; treatment options vary from radiation or medicines to surgery.

Schumer disclosed the diagnosis in the new edition of Jessica Yellin's "News Not Noise" newsletter, as her fans buzzed with questions about her face appearing "puffier" during the promotion tour for the second season of "Life & Beth."

The actress shared that she discovered that she was suffering from the condition while promoting her show, and after being diagnosed, she said that she feels like a completely new person and added, "Finding out I have the kind of Cushing that will just work itself out and I'm healthy was the greatest news imaginable."

Schumer said the online comments on her appearance made her realize something was wrong, adding, "It has been a crazy couple [of] weeks for me and my family. Aside from fears about my health, I also had to be on camera to have the internet chime in. But thank God for that. Because that's how I realized something was wrong."

Asked why she felt it necessary to post her "personal medical information," Schumer underscored: "I want to advocate for women's health. The shaming and criticism of our ever-changing bodies is something I have dealt with and witnessed for a long time. I want so much for women to love themselves and be relentless when fighting for their own health in a system that usually doesn't believe them."

Her diagnosis reminds one that every person is going through his or her own struggle, and she wishes that individuals could be gentler with each other and themselves. She first hinted at her health problems in an Instagram post on February 15, where she made mention of both her critics and her fight with endometriosis, which is an autoimmune disease.